Stay healthy:
Purified water is used in big-city hotels and restaurants, but bottled water is definitely recommended for outlying areas.
Malaria occurs in rural areas, Roatán and other Bay Islands.
Dengue fever is endemic in both urban and rural areas.
It is not recommended to buy much food in the streets (people who are selling food just by the sidewalk). Remember Honduran food can be spicy too, so be careful if you are not used to it.
Many travel agencies and different places will tell you that Honduras is a dangerous country concerning illnesses, this is not true. People are just as ill all over Latin America (nothing out of what is normal), just take the necessary precautions. HIV is a problem in Honduras so be careful as you would in your own country.
Carry a first aid kit and have contact phone numbers with you.
If hiking or spending significant time in the great outdoors, be prepared for a wide range of natural threats and nuisances including snakes, spiders, scorpions, and mosquitoes. On the upswing, however, you can actually pick fruit off the trees.
Respect:
Despite violence and widespread poverty, Hondurans are friendly people who appreciate a respectful manner. As well as this it is important to greet and even introduce yourself if you are asking a question to a stranger. Of course, like any other country, if you do need to ask a question from a stranger be careful but most of the time Hondurans will be friendly and more than happy to help you.
Cope:
Electricity is 110V/60Hz, as in the United States and Canada, however three-prong grounded plugs are not as common, so two-prong adapters come in handy.